HRP SU21-7: Research Opportunity with Dr. Stephen Crocker
This Health Research Program opportunity is with Dr. Stephen Crocker, Department of Neuroscience.
Project Description: Extracellular vesicles, also referred to as “exosomes” are a primordial form of intercellular communication. We have recently reported that extracellular vesicles isolated from blood plasma when administered to mice with neuroinflammation triggers a shift in their adaptive immune response and a spontaneous clinical disease phenotype more closely resembling human multiple sclerosis (Willis et al. 2019 Proc.Natl.Acad.Sci, 116:10488-493). This project will delve into the characterization of the autoimmune T cells initiated in this model using RNAseq, TCR profiling and flow cytometry techniques.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su21-7
For full details about the Health Research Program, visit https://ugradresearch.uconn.edu/hrp/