This Health Research Program opportunity is with Dr. Sivapriya Kailasan Vanaja, Department of Immunology.
Project Description: The primary focus of our research is to determine the mechanisms by which bacterial pathogens modulate host innate immune responses. Since innate immune responses play a crucial role in the clearance of infectious agents, it is natural that pathogens have developed strategies to inhibit the same. Our research aims to identify bacterial mechanisms that activate or inhibit innate immune activation. The summer research opportunity will focus on identifying virulence factors of two enteric pathogens, Enterohemorrhagic E. coli and Salmonella Typhimurium, that can activate or suppress a major innate immune pathway, the inflammasomes. The research strategy will involve working with bacterial mutants that lack specific virulence factors and determining their mode of action in innate immune cells such as macrophages.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su24-16
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.
HRP SU24-16: Research Opportunity with Dr. Sivapriya Kailasan Vanaja
This Health Research Program opportunity is with Dr. Sivapriya Kailasan Vanaja, Department of Immunology.
Project Description: The primary focus of our research is to determine the mechanisms by which bacterial pathogens modulate host innate immune responses. Since innate immune responses play a crucial role in the clearance of infectious agents, it is natural that pathogens have developed strategies to inhibit the same. Our research aims to identify bacterial mechanisms that activate or inhibit innate immune activation. The summer research opportunity will focus on identifying virulence factors of two enteric pathogens, Enterohemorrhagic E. coli and Salmonella Typhimurium, that can activate or suppress a major innate immune pathway, the inflammasomes. The research strategy will involve working with bacterial mutants that lack specific virulence factors and determining their mode of action in innate immune cells such as macrophages.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su24-16
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.