This Health Research Program opportunity is with Dr. Henry Smilowitz, Department of Cell Biology.
Project Description: 1. The Smilowitz lab in collaboration with Nanoprobes, Inc. pioneered the use of heavy atom nanoparticles to enhance radiation therapy of tumors. Going forward our lab will focus on a novel nanoparticle for radiation dose enhancement that may be better suited for translation to the clinic. Experiments will designed to understand how these nanoparticles can be used to maximize radiation dose enhancement of tumors--including tumor loading, distribution, mechanism of action and efficacy studies. 2. Collaborative studies are also ongoing in our lab on the targeting of nanoparticles to breast and brain tumors for therapeutic RNA delivery. 3. A third area of interest is the delivery of iodine nanoparticles to brain tumors in relation to the blood brain barrier. Experiments this summer will build on recent findings. 4. A new area of interest in the lab is therapy induced tumor dormancy (please see our 2023 publication in Cancer Immunology immunotherapy). Students who may have an interest in our lab are encouraged to look at the Smilowitz Lab Cell Biology blurb for our publications since 2000 and to set up an appointment to talk about projects in the lab.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su24-29
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.
HRP SU24-29: Research Opportunity with Dr. Henry Smilowitz
This Health Research Program opportunity is with Dr. Henry Smilowitz, Department of Cell Biology.
Project Description: 1. The Smilowitz lab in collaboration with Nanoprobes, Inc. pioneered the use of heavy atom nanoparticles to enhance radiation therapy of tumors. Going forward our lab will focus on a novel nanoparticle for radiation dose enhancement that may be better suited for translation to the clinic. Experiments will designed to understand how these nanoparticles can be used to maximize radiation dose enhancement of tumors--including tumor loading, distribution, mechanism of action and efficacy studies. 2. Collaborative studies are also ongoing in our lab on the targeting of nanoparticles to breast and brain tumors for therapeutic RNA delivery. 3. A third area of interest is the delivery of iodine nanoparticles to brain tumors in relation to the blood brain barrier. Experiments this summer will build on recent findings. 4. A new area of interest in the lab is therapy induced tumor dormancy (please see our 2023 publication in Cancer Immunology immunotherapy). Students who may have an interest in our lab are encouraged to look at the Smilowitz Lab Cell Biology blurb for our publications since 2000 and to set up an appointment to talk about projects in the lab.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su24-29
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.