This Health Research Program opportunity is with Dr. Xin-Ming Ma, Neuroscience.

Project Description: Understanding the mechanisms underlying depression and anxiety using a novel COP1 genetic mouse model.
Depression is often comorbid with anxiety. The Currently available antidepressants produce unsatisfactory results due to the limited understanding of the mechanisms underlying depression and anxiety. COP1 is a known risk factor for both conditions, and its protein is present in the brain areas associated with depression and anxiety. This study aims to determine whether COP1 deficiency or excess in the brain contributes to the development of depression and/or anxiety in a COP1 genetic mouse model. The findings will enhance our understanding of the mechanisms that underlie depression and anxiety.

For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrpsu25-19

For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/

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