This Health Research Program opportunity is with Dr. Danielle Rux, Department of Orthopedic Surgery.
Project Description: Our central research question is: how do developmental mechanisms that shape tissues early in life continue to influence tissue health and vulnerability to disease across the lifespan? The Rux lab focuses these efforts on the synovial joints and articular cartilage that are essential for all ranges of motion, but that are also highly susceptible to diseases such as arthritis that significantly reduce quality of life. Ongoing research projects are focused on how hedgehog signaling and the Hox genes function in joint development and disease. The selected student will learn to perform PCR, tissue histology, staining and imaging techniques from a novel genetically modified mouse model to test molecular mechanisms that control articular cartilage growth and maturation during embryonic and postnatal development.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su26-30
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.
HRP SU26-30: Research Opportunity with Dr. Danielle Rux
This Health Research Program opportunity is with Dr. Danielle Rux, Department of Orthopedic Surgery.
Project Description: Our central research question is: how do developmental mechanisms that shape tissues early in life continue to influence tissue health and vulnerability to disease across the lifespan? The Rux lab focuses these efforts on the synovial joints and articular cartilage that are essential for all ranges of motion, but that are also highly susceptible to diseases such as arthritis that significantly reduce quality of life. Ongoing research projects are focused on how hedgehog signaling and the Hox genes function in joint development and disease. The selected student will learn to perform PCR, tissue histology, staining and imaging techniques from a novel genetically modified mouse model to test molecular mechanisms that control articular cartilage growth and maturation during embryonic and postnatal development.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su26-30
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.