This Health Research Program opportunity is with Dr. Steven Chou, Department of Molecular Biology & Biophysics.
Project Description: Biochemical characterization of the membrane progesterone receptor mPRβ
The membrane progesterone receptors (mPRs) are a family of cell-surface receptors that mediate rapid, non-genomic progesterone signaling. Among the five known members, mPRβ remains poorly characterized. In this project, the student will overexpress and purify mPRβ using insect or mammalian cell systems, then investigate how progesterone and related small molecules influence its biochemical properties. The student will use techniques such as surface plasmon resonance and negative-stain electron microscopy to evaluate ligand-induced structural changes.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su26-6
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.
HRP SU26-6: Research Opportunity with Dr. Steven Chou
This Health Research Program opportunity is with Dr. Steven Chou, Department of Molecular Biology & Biophysics.
Project Description: Biochemical characterization of the membrane progesterone receptor mPRβ
The membrane progesterone receptors (mPRs) are a family of cell-surface receptors that mediate rapid, non-genomic progesterone signaling. Among the five known members, mPRβ remains poorly characterized. In this project, the student will overexpress and purify mPRβ using insect or mammalian cell systems, then investigate how progesterone and related small molecules influence its biochemical properties. The student will use techniques such as surface plasmon resonance and negative-stain electron microscopy to evaluate ligand-induced structural changes.
For full details about this Health Research Program opportunity, visit https://ugradresearch.uconn.edu/hrp/su26-6
For full details about the Health Research Program, visit ugradresearch.uconn.edu/hrp/
Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application. Before proceeding with your submission, please review their terms and privacy statements linked below.