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University of Connecticut - Quest Portal

Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)
Deadline Jun 29 2026 12:00 PM (EDT)
Description

National Institutes of Health (NIH)


The Office of the Vice President for Research (OVPR) is pleased to announce this limited submission funding opportunity/award. Limited submission programs allow only a select number of applicants from each institution.

All interested PIs must submit a Notice of Intent (NOI) through the UConn Quest Portal by the deadline listed below to be considered.

If the number of NOIs exceeds the sponsor’s limit, an internal competition will be conducted (see full process on our website). If the number of NOIs does not exceed the limit, eligible PIs who submitted an NOI by the deadline will be reviewed and typically approved to move forward.

Only PIs selected and approved by OVPR are eligible to submit to the sponsor.


Program Information: https://www.grants.gov/search-results-detail/360387

Quest Portal Link: https://quest.uconn.edu/prog/AOM-CC_FY27

Keywords: Children & Youth, Obesity, Pediatrics

Award Details: $5,000,000 ($1M/year for 5 years)

Number of UConn Applicants:  1 UConn – 1 UCH

Internal NOI Deadline: Monday, 6/29/2026 by 12 noon

Internal Pre-proposal (if necessary) Deadline: Monday, 7/13/2026 by 12 noon

Sponsor Full Proposal Deadline: 10/9/2026, 5 p.m. ET

Program information: This program invites applications from clinical centers to participate in a consortium to test AOM treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs.  Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will collaborate on the development of protocols, use of common measures and data elements, use of a central laboratory and standardized procedures to collect data and biospecimens, and data analyses and manuscripts.

Internal Competition Information: If a full internal competition is necessary, pre-proposals should be submitted that include:

  1. A two-page project narrative briefly describing the project, its key aims/objectives, the methodologies/approaches that will be used, and how the project goals align with the goals of the program. Please see the sponsor guidelines for details about program goals and application components.
  2. 1–2-page budget overview with justifications.
  3. Biosketches/brief CVs for key personnel.

For more information about the limited submission process, please check out our FAQ page.

For additional assistance, please contact the Office of the Vice President for Research at research@uconn.edu.

Follow UConn Research on Instagram & LinkedIn.

Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application.  Before proceeding with your submission, please review their terms and privacy statements linked below.

Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)


National Institutes of Health (NIH)


The Office of the Vice President for Research (OVPR) is pleased to announce this limited submission funding opportunity/award. Limited submission programs allow only a select number of applicants from each institution.

All interested PIs must submit a Notice of Intent (NOI) through the UConn Quest Portal by the deadline listed below to be considered.

If the number of NOIs exceeds the sponsor’s limit, an internal competition will be conducted (see full process on our website). If the number of NOIs does not exceed the limit, eligible PIs who submitted an NOI by the deadline will be reviewed and typically approved to move forward.

Only PIs selected and approved by OVPR are eligible to submit to the sponsor.


Program Information: https://www.grants.gov/search-results-detail/360387

Quest Portal Link: https://quest.uconn.edu/prog/AOM-CC_FY27

Keywords: Children & Youth, Obesity, Pediatrics

Award Details: $5,000,000 ($1M/year for 5 years)

Number of UConn Applicants:  1 UConn – 1 UCH

Internal NOI Deadline: Monday, 6/29/2026 by 12 noon

Internal Pre-proposal (if necessary) Deadline: Monday, 7/13/2026 by 12 noon

Sponsor Full Proposal Deadline: 10/9/2026, 5 p.m. ET

Program information: This program invites applications from clinical centers to participate in a consortium to test AOM treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs.  Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will collaborate on the development of protocols, use of common measures and data elements, use of a central laboratory and standardized procedures to collect data and biospecimens, and data analyses and manuscripts.

Internal Competition Information: If a full internal competition is necessary, pre-proposals should be submitted that include:

  1. A two-page project narrative briefly describing the project, its key aims/objectives, the methodologies/approaches that will be used, and how the project goals align with the goals of the program. Please see the sponsor guidelines for details about program goals and application components.
  2. 1–2-page budget overview with justifications.
  3. Biosketches/brief CVs for key personnel.

For more information about the limited submission process, please check out our FAQ page.

For additional assistance, please contact the Office of the Vice President for Research at research@uconn.edu.

Follow UConn Research on Instagram & LinkedIn.

Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application.  Before proceeding with your submission, please review their terms and privacy statements linked below.

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Deadline
Jun 29 2026 12:00 PM (EDT)